Generalized anxiety disorder is associated with unrealistic, excessive anxiety or worry about two or more life circumstances for a period of 6 months or longer. Some of the symptoms which may be present include: muscle tension, aches or soreness, feeling shaky, restlessness, palpitations or increased heart rate, sweating, shortness of breath, dry mouth, dizziness, diarrhea, nausea, frequent urination, irritability, and/or trouble falling or staying asleep.
Some of the medication listed down below can reduce or get rid of those symptoms.
Alprazolam (Xanax XR, Niravam), is an anti-anxiety medication in the benzodiazepine family, the same family that includes diazepam (Valium), clonazepam (Klonopin), lorazepam (Ativan), flurazepam (Dalmane), and others. Alprazolam and other benzodiazepines act by enhancing the effects of gamma-aminobutyric acid (GABA) in the brain. GABA is a neurotransmitter (a chemical that nerve cells use to communicate with each other) that inhibits activity in the brain. It is believed that excessive activity in the brain may cause anxiety or other psychiatric disorders. The FDA approved alprazolam in October 1981.
Xanax Commonly Prescribed for Generalized anxiety disorder (IR), Panic disorder (IR and XR), Other anxiety disorders, Anxiety associated with depression, Premenstrual dysphoric disorder, Insomnia, Acute mania (adjunctive), Acute psychosis (adjunctive), Catatonia
The effect of benzodiazepines is quite profound. They work, by “suppressing the output of neurotransmitters that interpret fear.” In other words, they eliminate our ability to feel danger, which to someone with a panic disorder may mean the abatement of an anxiety attack. Or, for someone who’s taken four times the recommended dosage and mixed that with alcohol, could mean the beginnings of something much more catastrophic.
Klonopin (clonazepam) is a benzodiazepine officially indicated for management of seizure disorders and panic disorder. The use of a drug for its approved indications is called its labeled use. In clinical practice, however, physicians often prescribe medications for unlabeled (“off-label”) uses when published clinical studies, case reports, or their own clinical experiences support the efficacy and safety of those treatments. Physicians may use Klonopin outside its approved indications to treat social anxiety disorder, posttraumatic stress disorder, agitation in acute psychosis and mania, and premenstrual syndrome. As with other benzodiazepines, Klonopin is associated with dependence and abuse and is regulated as a controlled substance by state and federal laws.
The onset of action usually occurs within 20 to 60 minutes. Although you may experience beneficial effects from clonazepam within a few days of starting to take the medication, it often takes several weeks to get the full effect of the medication. Your healthcare provider may also need to gradually adjust the dose over a period of several weeks to find the dose that works best for you.
Diazepam is a benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
Valium is mainly used to help treat anxiety, alcohol withdrawal and/or insomnia. Valium is also used to sedate or tranquilize people or to induce amnesia before certain medical procedures. Valium is prescribed by doctors for a wide range of medical conditions. These include:
Diazepam should be used with caution in patients with pulmonary disease. Additionally, avoid coadministration with other CNS depressants, especially opioids, unless no other alternatives are available as coadministration significantly increases the risk for respiratory depression, low blood pressure, and death. According to the manufacturer, oral diazepam tablets are contraindicated for use in those with severe respiratory insufficiency or sleep apnea syndrome. Diazepam should be used with caution in other pulmonary diseases as well including severe chronic obstructive pulmonary disease (COPD), sleep apnea, asthma, or pneumonia because the drug can exacerbate ventilatory failure. Lower doses are recommended in patients with chronic respiratory insufficiency.
Librium capsules contain the active ingredient chlordiazepoxide, which is a type of medicine called a benzodiazepine. Chlordiazepoxide is also available without a brand name, ie as the generic medicine. Benzodiazepines are used for their sedative, anxiety-relieving and muscle-relaxing effects.
Chlordiazepoxide works by acting on receptors in the brain called GABA receptors. This causes the release of a neurotransmitter called GABA in the brain.
Neurotransmitters are chemicals that are stored in nerve cells in the brain and nervous system. They are involved in transmitting messages between the nerve cells. GABA is a neurotransmitter that acts as a natural ‘nerve-calming’ agent. It helps keep the nerve activity in the brain in balance, and is involved in inducing sleepiness, reducing anxiety and relaxing muscles.
As chlordiazepoxide increases the activity of GABA in the brain, it increases its calming effect and results in sleepiness, a decrease in anxiety and relaxation of muscles.
Chlordiazepoxide is used for the short-term treatment of severe anxiety, including anxiety associated with insomnia. Chlordiazepoxide decreases the time taken to fall asleep and nocturnal awakenings, as well as increasing the total amount of time spent sleeping. However, it is only suitable for short-term treatment of anxiety and insomnia as it has a high potential for dependence and addiction. As chlordiazepoxide remains active in the body for many hours, drowsiness may also last into the next day.
Chlordiazepoxide is used in the treatment of alcoholism for its sedating and anxiety-relieving effects, which help relieve the symptoms of acute alcohol withdrawal.
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